Science is at the core of everything we do at Neutrove. Our supplements are backed by research and clinical trials to ensure you get exactly what your body needs for optimal health. We go beyond simply listing ingredients—diving into their molecular foundations and how they work together to deliver real results.
This page offers an in-depth look at the science behind our ingredients, reflecting our commitment to evidence-based formulas and your long-term well-being. From the role of Resveratrol in promoting longevity to the metabolic support offered by Berberine, explore how our supplements can elevate your health journey.
The Science
Explore the science behind our supplements. We break down the research, dosages, and molecular foundations to show why every detail matters for real results. True efficacy comes from evidence-based formulations, and this page reflects that commitment.
The Science of Longevity
A clinical trial in the Journal of Clinical Endocrinology & Metabolism (2008) showed that berberine supplementation reduced fasting blood glucose and improved insulin sensitivity in patients with type 2 diabetes (PubMed). Another randomized trial in Metabolism (2008) reported that berberine lowered total cholesterol, LDL cholesterol, and triglycerides while raising HDL cholesterol in patients with high cholesterol (PubMed). A 2015 meta-analysis in the Journal of Ethnopharmacology confirmed that berberine reduced blood glucose, improved lipid profiles, and supported weight management in people with metabolic syndrome (PubMed).
More recently, a 2020 meta-analysis published in Phytotherapy Research found that berberine reduced BMI and inflammatory markers like C-reactive protein (PubMed). A 2024 meta-analysis in BMC Translational Medicine further demonstrated that berberine improved insulin sensitivity, liver enzyme levels, and lipid metabolism in patients with non-alcoholic fatty liver disease (BMC).
If you’d like to explore more studies and data, visit our Science section, where we share the research and data behind every ingredient we use.
A randomized controlled trial in the European Journal of Nutrition (2015) showed that daily oral glutathione significantly raised blood glutathione levels and improved immune markers compared with placebo (PubMed). This provides direct evidence that supplementation can enhance the body’s antioxidant defenses.
In liver health, a pilot clinical study in BMC Gastroenterology (2017) found that oral glutathione supplementation improved ALT levels and reduced hepatic fat in patients with nonalcoholic fatty liver disease (PMC). These findings suggest glutathione may protect the liver from oxidative stress and support recovery in metabolic conditions.
Mechanistically, glutathione is critical for mitochondrial protection and redox balance. A review in Frontiers in Pharmacology (2017) highlighted its role in reducing oxidative stress, regulating inflammation, and preventing mitochondrial dysfunction across chronic diseases (PMC). Together, this evidence underscores glutathione’s importance in immune defense, liver health, and cellular longevity.
If you’d like to explore more studies and data, visit our Science section, where we share the research and data behind every ingredient we use.
A landmark meta-analysis in Mayo Clinic Proceedings (2014) concluded that CoQ10 supplementation improved outcomes in patients with heart failure, including better ejection fraction and reduced cardiovascular mortality (PMC3742297). The Q-SYMBIO randomized controlled trial in the European Heart Journal (2014) further showed that CoQ10 reduced adverse cardiovascular events in chronic heart failure patients (PubMed).
A review in Frontiers in Physiology (2018) highlighted CoQ10’s role in improving mitochondrial efficiency and reducing oxidative stress in aging populations (Frontiers). Similarly, a 2022 meta-analysis in Frontiers in Pharmacology found that CoQ10 supplementation significantly reduced fatigue symptoms across randomized controlled trials (Frontiers).
In reproductive health, a review in the International Journal of Molecular Sciences (2021) reported that CoQ10 supplementation improved ovarian response and egg quality in women undergoing fertility treatment, likely by
protecting mitochondria and reducing oxidative stress (MDPI). Together, these findings reinforce CoQ10’s importance in cardiovascular health, energy metabolism, and healthy aging.
If you’d like to explore more studies and data, visit our Science section,
where we share the research and data behind every ingredient we use.
A clinical trial published in the Journal of Clinical Psychopharmacology (2015) showed that curcumin supplementation improved mood and reduced fatigue in patients with major depressive disorder (PubMed), demonstrating its neuroprotective and anti-inflammatory properties. In metabolic health, a randomized controlled trial in the American Journal of Cardiology (2012) found that curcumin supplementation reduced the incidence of heart attacks after bypass surgery by lowering inflammatory markers and oxidative stress.
Resveratrol has also demonstrated strong clinical relevance. A trial in the Journal of Clinical Endocrinology & Metabolism (2011) reported that resveratrol improved insulin sensitivity and reduced oxidative stress in obese men (MDPI review including clinical data). More recently, a study in PLOS Biology (2013) demonstrated that resveratrol activates SIRT1, enhancing mitochondrial biogenesis and cellular energy production (PLOS Biology). A 2022 review in Frontiers in Nutrition
further confirmed resveratrol’s role in SIRT1 activation, oxidative
stress reduction, and mitochondrial efficiency, supporting its relevance
in healthy aging research (PMC9756291).
If you’d like to explore more studies and data, visit our Science section, where we share the research and data behind every ingredient we use.
Magnesium is essential for metabolic balance and energy
production. A dose–response meta-analysis published in Diabetes Care
(2011) found that higher magnesium intake was linked to a significant
reduction in type 2 diabetes risk, confirming its role in glucose
regulation and insulin sensitivity. (Pubmed)
It also contributes to neurological and sleep health. A double-blind
placebo-controlled trial in the Journal of Research in Medical Sciences
(2012) showed that magnesium supplementation improved sleep time,
efficiency, and onset latency in older adults with insomnia, likely by
influencing melatonin and cortisol levels. (Pubmed)
In cardiovascular health, a meta-analysis of randomized controlled trials published in Hypertension (2016) reported that magnesium supplementation led to clinically meaningful reductions in blood pressure, supporting its role in vascular function and long-term heart protection. (Pubmed)
If you’d like to explore more studies and data, visit our Science section, where we share the research and data behind every ingredient we use.
Start Your Longevity Routine Now!
Now that you understand the science behind our supplements, you’re empowered to take the next step in your health journey. Each supplement is backed by research and crafted to enhance your well-being—because making informed choices means investing in a healthier future.
Neutrove Ingredients Are Free From
Unnecessary binders, fillers & preservatives
Trans fat & hydrogenated oils
Coatings & Shellacs
Magnesium Stearate
Genetically modified organisms (GMO)
Artificial colors, flavors & sweeteners